Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody
The VH6-1 class of antibodies includes some of the broadest and most potent antibodies that neutralize influenza A virus.Here, Vacuum Turbo Tool we elicit and isolate anti-idiotype antibodies against germline versions of VH6-1 antibodies, use these to sort human leukocytes, and isolate a new VH6-1-class member, antibody L5A7, which potently neutral